Programs

MAJOR GLOBAL HEALTH CARE CONCERN

T deficiency is a prevalent medical condition. T deficiency can arise for a number of reasons:

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Primary and Secondary Hypogonadism
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Acquired Hypogonadism

(e.g. in chemotherapy, AIDS, chronic lung disease and renal failure, cirrhosis, opioid treatment and critical illness).

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Late (or Adult) Onset Hypogonadism

The prevalence of low T levels in men may be linked with conditions such as:

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Reduced Libido & Infertility
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Obesity
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Diabetes Type 2 & Metabolic Syndrome
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Klinefelter Syndrome: a genetic condition that occurs when a boy is born with an extra X chromosome (XXY)
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High blood sugar, low mood, osteoporosis, chronic obstructive pulmonary disease, chronic kidney disease, decreased muscle strength

Source: Lancet Diabetes Endocrinol . 2024 Oct;12(10):761-774; Cureus 2025 Feb 9;17(2):e78785

The problem

Current treatments may carry high risk for patients treated with TRT:

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High blood pressure

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Although controversial, it may promote prostate tumorigenesis

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May reduce intratesticular T
and sperm numbers
leading to infertility

ACESIS’ SOLUTION

Our proprietary family of testosterone-inducing peptides is designed to provide a safe and effective treatment for male hypogonadism (pending rigorous clinical trials and regulatory approvals).

Comparison of acesis’s novel solution with marketed low t treatments

Acesis’ plans to fulfil an unmet market need
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*”A black box warning is the FDA’s most stringent warning for drugs and medical devices on the market alerting the public and health care providers to serious side effects, such as injury or death” https://www.drugwatch.com/fda/black-box-warnings

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Market opportunity

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